Preprints
https://doi.org/10.5194/amt-2024-107
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/amt-2024-107
© Author(s) 2024. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
24 Jul 2024
| 24 Jul 2024
Status: this preprint is currently under review for the journal AMT.
An interlaboratory comparison to quantify oxidative potential measurement in aerosol particles: challenges and recommendations for harmonisation
Abstract. This paper presents the findings from a collaborative interlaboratory comparison exercise designed to assess oxidative potential (OP) measurements conducted by 20 laboratories worldwide. This study represents an innovative effort as the first exercise specifically aimed at harmonising this type of OP assay, setting a new benchmark in the field.
Over the last decade, there has been a noticeable increase in OP studies, with numerous research groups investigating the effects of exposure to air pollution particles through the evaluation of OP levels. However, the absence of standardised methods for OP measurements has resulted in variability in results across different groups, rendering meaningful comparisons challenging. To address this issue, this study engages in an international effort to compare OP measurements using a simplified method (with a dithiothreitol (DTT) assay).
Here, we quantify the OP in liquid samples to focus on the protocol measurement itself, while future ILCs should aim to assess the full-chain process, including the sample extraction. We analyse the similarities and discrepancies observed in the results, identifying the critical parameters (such as the instrument used, the use of a simplified protocol, the delivery and analysis time) that could influence OP measurements, and provide recommendations for future studies and interlaboratory comparisons. Even if other crucial aspects, such as sampling PM methods, sample storage, extraction methods and conditions, and the evaluation of other OP assays, still need to be standardised. This collaborative approach enhances the robustness of the OP-DTT assay and paves the way for future studies to build on a unified framework. This pioneering work concludes that interlaboratory comparisons provide essential insights into the OP metric and are crucial to move toward the harmonisation of OP measurements.
How to cite. Dominutti, P. A., Jaffrezo, J.-L., Marsal, A., Mhadhbi, T., Elazzouzi, R., Rak, C., Cavalli, F., Putaud, J.-P., Bougiatioti, A., Mihalopoulos, N., Paraskevopoulou, D., Mudway, I. S., Nenes, A., Daellenbach, K. R., Banach, C., Campbell, S. J., Cigánková, H., Contini, D., Evans, G., Georgopoulou, M., Ghanem, M., Glencross, D. A., Guascito, M. R., Herrmann, H., Iram, S., Jovanović, M., Jovašević-Stojanović, M., Kalberer, M., Kooter, I. M., Paulson, S. E., Patel, A., Perdrix, E., Pietrogrande, M. C., Mikuška, P., Sauvain, J.-J., Seitanidi, A., Shahpoury, P., Souza, E. J. S., Steimer, S., Stevanovic, S., Suarez, G., Subramanian, P. S. G., Utinger, B., van Os, M. F., Verma, V., Wang, X., Weber, R. J., Yang, Y., Querol, X., Hoek, G., Harrison, R. M., and Uzu, G.: An interlaboratory comparison to quantify oxidative potential measurement in aerosol particles: challenges and recommendations for harmonisation, Atmos. Meas. Tech. Discuss. [preprint], https://doi.org/10.5194/amt-2024-107, in review, 2024.
Publisher's note: Copernicus Publications remains neutral with regard to jurisdictional claims made in the text, published maps, institutional affiliations, or any other geographical representation in this preprint. The responsibility to include appropriate place names lies with the authors.
Download & links
- Preprint
(2048 KB) - Metadata XML
-
Supplement
(2323 KB) - BibTeX
- EndNote
Status: open (until 28 Aug 2024)
Comment types: AC – author | RC – referee | CC – community | EC – editor | CEC – chief editor
| : Report abuse
Viewed
Total article views: 85 (including HTML, PDF, and XML)
Cumulative views and downloads
(calculated since 24 Jul 2024)
| HTML | XML | Total | Supplement | BibTeX | EndNote | |
|---|---|---|---|---|---|---|
| 65 | 17 | 3 | 85 | 6 | 1 | 1 |
- HTML: 65
- PDF: 17
- XML: 3
- Total: 85
- Supplement: 6
- BibTeX: 1
- EndNote: 1
Viewed (geographical distribution)
Total article views: 85 (including HTML, PDF, and XML)
Thereof 85 with geography defined
and 0 with unknown origin.
| Country | # | Views | % |
|---|
| Total: | 0 |
| HTML: | 0 |
| PDF: | 0 |
| XML: | 0 |
- 1
1
Latest update: 26 Jul 2024
Pamela A. Dominutti
University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
Jean-Luc Jaffrezo
University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
Anouk Marsal
University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
Takoua Mhadhbi
University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
Rhabira Elazzouzi
University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
Camille Rak
University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
Fabrizia Cavalli
European Commission, Joint Research Centre (JRC), Ispra, Italy
Jean-Philippe Putaud
European Commission, Joint Research Centre (JRC), Ispra, Italy
Aikaterini Bougiatioti
Institute for Environmental Research and Sustainable Development, National Observatory of Athens, Lofos Koufou, P. Penteli, Athens, 15236, Greece
Nikolaos Mihalopoulos
Institute for Environmental Research and Sustainable Development, National Observatory of Athens, Lofos Koufou, P. Penteli, Athens, 15236, Greece
Environmental Chemical Processes Laboratory, Department of Chemistry, University of Crete, Heraklion, 71003, Greece
Despina Paraskevopoulou
Institute for Environmental Research and Sustainable Development, National Observatory of Athens, Lofos Koufou, P. Penteli, Athens, 15236, Greece
Ian S. Mudway
MRC Centre for Environment and Health, and the National Institute of Health Research, Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK
Athanasios Nenes
Center for the Study of Air Quality and Climate Change, Institute of Chemical Engineering Sciences, Foundation for Research and Technology Hellas, Patras, Greece 26504
Laboratory of Atmospheric Processes and their Impacts, Institute of Environmental Engineering, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland, 1015
Kaspar R. Daellenbach
Laboratory of Atmospheric Chemistry, Paul Scherrer Institute, 5232 Villigen PSI, Switzerland
Catherine Banach
Department of Atmospheric and Oceanic Sciences, University of California at Los Angeles, 520 Portola Plaza, Los Angeles, California, 90095, United States
Steven J. Campbell
MRC Centre for Environment and Health, Environmental Research Group, Imperial College London, 86 Wood Lane, London W12 0BZ, UK
Hana Cigánková
Department of Environmental Analytical Chemistry, Institute of Analytical Chemistry, Czech Academy of Sciences, Veveří 97, 60200 Brno, Czech Republic
Daniele Contini
Institute of Atmospheric Sciences and Climate, ISAC-CNR, Str. Prv. Lecce-Monteroni km 1.2, 73100 Lecce, Italy
Greg Evans
Southern Ontario Centre for Atmospheric Aerosol Research, University of Toronto, Toronto, M5S 3E5, Canada
Maria Georgopoulou
Center for the Study of Air Quality and Climate Change, Institute of Chemical Engineering Sciences, Foundation for Research and Technology Hellas, Patras, Greece 26504
Manuella Ghanem
Department of Pollutant Metrology, Institut National de Recherche et de Sécurité (INRS), 54500 Vandœuvrelès-Nancy, France
Drew A. Glencross
MRC Centre for Environment and Health, and the National Institute of Health Research, Health Protection Research Unit in Environmental Exposures and Health, Imperial College London, London, UK
Maria Rachele Guascito
Institute of Atmospheric Sciences and Climate, ISAC-CNR, Str. Prv. Lecce-Monteroni km 1.2, 73100 Lecce, Italy
Department of Environmental and Biological Sciences and Technologies (DISTEBA), University of Salento, Lecce 73100, Italy
Hartmut Herrmann
Atmospheric Chemistry Department (ACD), Leibniz Institute for Tropospheric Research (TROPOS), Permoserstraße 15, 04318 Leipzig, Germany
Saima Iram
School of Engineering, Deakin University, VIC 3216, Australia
Maja Jovanović
Vinča Institute of Nuclear Sciences – National Institute of the Republic of Serbia, University of Belgrade, 11 351 Belgrade, Serbia
Milena Jovašević-Stojanović
Vinča Institute of Nuclear Sciences – National Institute of the Republic of Serbia, University of Belgrade, 11 351 Belgrade, Serbia
Markus Kalberer
Department of Environmental Sciences, University of Basel, 4056 Basel, Switzerland
Ingeborg M. Kooter
TNO Environmental Modelling, Sensing and Analysis, Princetonlaan 6-8, 3584 CB Utrecht, Netherlands
deceased
Suzanne E. Paulson
Department of Atmospheric and Oceanic Sciences, University of California at Los Angeles, 520 Portola Plaza, Los Angeles, California, 90095, United States
Anil Patel
Department of Environmental Science, Stockholm University, Stockholm, 11418, Sweden
Bolin Centre for Climate Research, Stockholm, 11418, Sweden
now at: Department of Atmospheric and Oceanic Sciences, University of California at Los Angeles, Los Angeles, CA 90095-1565, USA
Esperanza Perdrix
IMT Nord Europe, Institut Mines-Télécom, Univ. Lille, Centre for Energy and Environment, F-59000 Lille, France
Maria Chiara Pietrogrande
Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, Via Fossato di Mortara 17/19, 44121 Ferrara, Italy
Pavel Mikuška
Department of Environmental Analytical Chemistry, Institute of Analytical Chemistry, Czech Academy of Sciences, Veveří 97, 60200 Brno, Czech Republic
Jean-Jacques Sauvain
Center for Primary Care and Public Health (Unisanté), Department of Occupational and Environment Health (DSTE), University of Lausanne, Switzerland
Aikaterina Seitanidi
Center for the Study of Air Quality and Climate Change, Institute of Chemical Engineering Sciences, Foundation for Research and Technology Hellas, Patras, Greece 26504
Pourya Shahpoury
Environmental and Life Sciences, Trent University, Peterborough, Canada
Eduardo J. S. Souza
Atmospheric Chemistry Department (ACD), Leibniz Institute for Tropospheric Research (TROPOS), Permoserstraße 15, 04318 Leipzig, Germany
Sarah Steimer
Department of Environmental Science, Stockholm University, Stockholm, 11418, Sweden
Bolin Centre for Climate Research, Stockholm, 11418, Sweden
Svetlana Stevanovic
School of Engineering, Deakin University, VIC 3216, Australia
Guillaume Suarez
Center for Primary Care and Public Health (Unisanté), Department of Occupational and Environment Health (DSTE), University of Lausanne, Switzerland
P. S. Ganesh Subramanian
Department of Civil and Environmental Engineering, University of Illinois at Urbana-Champaign, 205 North Mathews Avenue, Urbana, IL, 61801, United States
Battist Utinger
Department of Environmental Sciences, University of Basel, 4056 Basel, Switzerland
Marloes F. van Os
TNO Environmental Modelling, Sensing and Analysis, Princetonlaan 6-8, 3584 CB Utrecht, Netherlands
Vishal Verma
Department of Civil and Environmental Engineering, University of Illinois at Urbana-Champaign, 205 North Mathews Avenue, Urbana, IL, 61801, United States
Xing Wang
Southern Ontario Centre for Atmospheric Aerosol Research, University of Toronto, Toronto, M5S 3E5, Canada
Rodney J. Weber
School of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332, United States
Yuhan Yang
School of Earth and Atmospheric Sciences, Georgia Institute of Technology, Atlanta, Georgia 30332, United States
Xavier Querol
Institute of Environmental Assessment and Water Research (IDAEA-CSIC), 08034 Barcelona, Spain
Gerard Hoek
Institute for Risk Assessment Sciences, Utrecht University, Utrecht, 3584CM, the Netherlands
Roy M. Harrison
Division of Environmental Health and Risk Management, School of Geography Earth and Environmental Sciences, Edgbaston, Birmingham, UK, B15 2TT, United Kingdom
Department of Environmental Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
University Grenoble Alpes, CNRS, INRAE, IRD, INP-G, IGE (UMR 5001), 38000 Grenoble, France
now at: Department of Atmospheric and Oceanic Sciences, University of California at Los Angeles, Los Angeles, CA 90095-1565, USA
Short summary
In this work, 20 labs worldwide collaborated to evaluate the measurement of air pollution's oxidative potential (OP), a key indicator of its harmful effects. The study aimed to identify disparities in the widely used OP DTT assay and assess the consistency of OP among labs using the same protocol. The results showed that half of the labs achieved acceptable results. However, variability was also found, highlighting the need for standardization in OP procedures.
In this work, 20 labs worldwide collaborated to evaluate the measurement of air pollution's...