Articles | Volume 18, issue 11
https://doi.org/10.5194/amt-18-2425-2025
https://doi.org/10.5194/amt-18-2425-2025
Research article
 | 
05 Jun 2025
Research article |  | 05 Jun 2025

A solid-state infrared laser for two-step desorption–ionization processes in single-particle mass spectrometry

Marco Schmidt, Haseeb Hakkim, Lukas Anders, Aleksandrs Kalamašņikovs, Thomas Kröger-Badge, Robert Irsig, Norbert Graf, Reinhard Kelnberger, Johannes Passig, and Ralf Zimmermann

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Short summary
Laser desorption of individual particles prior to ionization is the key to reveal their organic composition. The CO2 lasers required are bulky and maintenance-intensive, limiting their use in the field. We have developed a compact solid-state IR laser that is easily aligned with the particle beam. Mass spectra and hit rates are similar to those of the CO2 laser. For combined characterization of organic and inorganic particle compositions, both lasers are superior to conventional single UV pulses.
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