A method for measuring total aerosol oxidative potential (OP) with the dithiothreitol (DTT) assay and comparisons between an urban and roadside site of water-soluble and total OP

Gao, Dong; Fang, Ting; Verma, Vishal; Zeng, Linghan; Weber, Rodney J.

doi:https://doi.org/10.5194/amt-10-2821-2017

Articles | Volume 10, issue 8

https://doi.org/10.5194/amt-10-2821-2017

© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 3.0 License.

https://doi.org/10.5194/amt-10-2821-2017

© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 3.0 License.

Articles | Volume 10, issue 8

Research article

|

08 Aug 2017

Research article |

| 08 Aug 2017

A method for measuring total aerosol oxidative potential (OP) with the dithiothreitol (DTT) assay and comparisons between an urban and roadside site of water-soluble and total OP

Dong Gao, Ting Fang, Vishal Verma, Linghan Zeng, and Rodney J. Weber

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Final revised paper (published on 08 Aug 2017)
Supplement to the final revised paper
Preprint (discussion started on 21 Apr 2017)
Supplement to the preprint

Interactive discussion

Status: closed

AC: Author comment | RC: Referee comment | SC: Short comment | EC: Editor comment

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- Supplement

RC1: 'Revier comments', Anonymous Referee #1, 08 May 2017
RC2: 'Referee Report', Anonymous Referee #2, 09 May 2017
RC3: 'Review comments', Anonymous Referee #4, 10 May 2017
RC4: 'comments on discussion paper', Anonymous Referee #3, 15 May 2017
AC1: 'Responses to comments', Dong Gao, 07 Jul 2017

Peer-review completion

AR: Author's response | RR: Referee report | ED: Editor decision

AR by Dong Gao on behalf of the Authors (07 Jul 2017) Author's response Manuscript

ED: Publish as is (10 Jul 2017) by Pierre Herckes

AR by Dong Gao on behalf of the Authors (11 Jul 2017)

Short summary

This work compares three methods to determine the optimal approach for quantifying the total oxidative potential (OP) of fine particles collected with filters using the dithiothreitol (DTT) assay. An automated system has been developed to facilitate the total OP measurements for use in generation of large data sets needed for epidemiology studies. The results from this study show that the water-insoluble components contribute to PM_2.5 OP and the related DTT-active species are largely secondary.