Articles | Volume 14, issue 12
https://doi.org/10.5194/amt-14-7579-2021
https://doi.org/10.5194/amt-14-7579-2021
Research article
 | 
07 Dec 2021
Research article |  | 07 Dec 2021

A semi-automated instrument for cellular oxidative potential evaluation (SCOPE) of water-soluble extracts of ambient particulate matter

Sudheer Salana, Yixiang Wang, Joseph V. Puthussery, and Vishal Verma

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Latest update: 27 Feb 2024
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Short summary
Oxidative potential (OP) of particulate matter (PM) is an important indicator of PM toxicity. However, no automated instrument has ever been developed to provide a rapid high-throughput analysis of cell-based OP measurements. Here, we developed a semi-automated instrument, the first of its kind, for measuring oxidative potential using rat alveolar cells. We also developed a dataset on the intrinsic cellular OP of several compounds commonly known to be present in ambient PM.