Articles | Volume 9, issue 8
https://doi.org/10.5194/amt-9-3969-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
https://doi.org/10.5194/amt-9-3969-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
Research article
| 
23 Aug 2016
Research article |
| 23 Aug 2016
Clustering, methodology, and mechanistic insights into acetate chemical ionization using high-resolution time-of-flight mass spectrometry
Department of Chemistry, Colorado State University, 1872 Campus Delivery,
Fort Collins, CO 80523, USA
Delphine K. Farmer
CORRESPONDING AUTHOR
Department of Chemistry, Colorado State University, 1872 Campus Delivery,
Fort Collins, CO 80523, USA
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- Characterization of a high detection-sensitivity atmospheric pressure interface time-of-flight mass spectrometer F. Schmidt-Ott et al. https://doi.org/10.5194/amt-18-7075-2025
- Computational Comparison of Acetate and Nitrate Chemical Ionization of Highly Oxidized Cyclohexene Ozonolysis Intermediates and Products N. Hyttinen et al. https://doi.org/10.1021/acs.jpca.6b12654
- Decomposition of Clusters of Oxygenated Compounds with NO3– by Applying Voltage Scanning to Chemical Ionization Mass Spectrometry in Steady-State Experiments H. Wang et al. https://doi.org/10.1021/acs.estlett.4c00276
- Mass Spectrometry Analysis in Atmospheric Chemistry J. Laskin et al. https://doi.org/10.1021/acs.analchem.7b04249
- Reactive Uptake of Hydroperoxymethyl Thioformate to Sodium Chloride and Sodium Iodide Aerosol Particles C. Jernigan et al. https://doi.org/10.1021/acs.jpca.2c03222
- A review of microbial and chemical assessment of indoor surfaces V. Mihucz et al. https://doi.org/10.1080/05704928.2021.1995870
- Atmospheric OH Oxidation of Three Chlorinated Aromatic Herbicides T. Murschell & D. Farmer https://doi.org/10.1021/acs.est.7b06025
- Secondary Organic Aerosol Formation from Healthy and Aphid-Stressed Scots Pine Emissions C. Faiola et al. https://doi.org/10.1021/acsearthspacechem.9b00118
- Non-radioactive Chemical Ionization Mass Spectrometry Using Acetic Acid–Acetate Cluster as a Reagent Ion for the Real-time Measurement of Acids and Hydroperoxides S. Inomata & J. Hirokawa https://doi.org/10.1246/cl.160828
- Isoprene versus Monoterpenes as Gas-Phase Organic Acid Precursors in the Atmosphere M. Link et al. https://doi.org/10.1021/acsearthspacechem.1c00093
- Sources of isocyanic acid (HNCO) indoors: a focus on cigarette smoke R. Hems et al. https://doi.org/10.1039/C9EM00107G
- Characterisation of the transfer of cluster ions through an atmospheric pressure interface time-of-flight mass spectrometer with hexapole ion guides M. Leiminger et al. https://doi.org/10.5194/amt-12-5231-2019
- Tropospheric sources and sinks of gas-phase acids in the Colorado Front Range J. Mattila et al. https://doi.org/10.5194/acp-18-12315-2018
- Measuring Biosphere–Atmosphere Exchange of Short-Lived Climate Forcers and Their Precursors D. Farmer & M. Riches https://doi.org/10.1021/acs.accounts.0c00203
- Product ion distributions using H3O+ proton-transfer-reaction time-of-flight mass spectrometry (PTR-ToF-MS): mechanisms, transmission effects, and instrument-to-instrument variability M. Link et al. https://doi.org/10.5194/amt-18-1013-2025
- Modelling indoor radical chemistry during the HOMEChem campaign F. Østerstrøm et al. https://doi.org/10.1039/D4EM00628C
- Chemical ionization mass spectrometry: Developments and applications for on-line characterization of atmospheric aerosols and trace gases Y. Zhang et al. https://doi.org/10.1016/j.trac.2023.117353
- The persistence of smoke VOCs indoors: Partitioning, surface cleaning, and air cleaning in a smoke-contaminated house J. Li et al. https://doi.org/10.1126/sciadv.adh8263
- Atmospheric OH oxidation chemistry of trifluralin and acetochlor T. Murschell & D. Farmer https://doi.org/10.1039/C8EM00507A
- Ion-neutral Clustering of Bile Acids in Electrospray Ionization Across UPLC Flow Regimes P. Brophy et al. https://doi.org/10.1007/s13361-017-1878-6
- Coupling a gas chromatograph simultaneously to a flame ionization detector and chemical ionization mass spectrometer for isomer-resolved measurements of particle-phase organic compounds C. Bi et al. https://doi.org/10.5194/amt-14-3895-2021
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- SOA and gas phase organic acid yields from the sequential photooxidation of seven monoterpenes B. Friedman & D. Farmer https://doi.org/10.1016/j.atmosenv.2018.06.003
- Seasonal Flux Measurements over a Colorado Pine Forest Demonstrate a Persistent Source of Organic Acids S. Fulgham et al. https://doi.org/10.1021/acsearthspacechem.9b00182
- Analytical Challenges and Opportunities For Indoor Air Chemistry Field Studies D. Farmer https://doi.org/10.1021/acs.analchem.9b00277
- Quantification of isomer-resolved iodide chemical ionization mass spectrometry sensitivity and uncertainty using a voltage-scanning approach C. Bi et al. https://doi.org/10.5194/amt-14-6835-2021
- Surface reservoirs dominate dynamic gas-surface partitioning of many indoor air constituents C. Wang et al. https://doi.org/10.1126/sciadv.aay8973
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- Correcting bias in log-linear instrument calibrations in the context of chemical ionization mass spectrometry C. Bi et al. https://doi.org/10.5194/amt-14-6551-2021
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- Tracking indoor volatile organic compounds with online mass spectrometry W. Liu et al. https://doi.org/10.1016/j.trac.2023.117514
- Multiphase Chemistry Controls Inorganic Chlorinated and Nitrogenated Compounds in Indoor Air during Bleach Cleaning J. Mattila et al. https://doi.org/10.1021/acs.est.9b05767
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Saved (final revised paper)
Latest update: 05 Jun 2026
Short summary
We describe voltage scanning methodologies using a high-resolution time-of-flight chemical ionization mass spectrometer (HR-TOF-CIMS) with acetate reagent ions to control for clustering observed in the mass spectrum. Operational considerations related to atmospheric measurements of carboxylic acids using acetate chemical ionization are discussed.
We describe voltage scanning methodologies using a high-resolution time-of-flight chemical...
