Articles | Volume 14, issue 10
Research article
25 Oct 2021
Research article |  | 25 Oct 2021

Quantification of isomer-resolved iodide chemical ionization mass spectrometry sensitivity and uncertainty using a voltage-scanning approach

Chenyang Bi, Jordan E. Krechmer, Graham O. Frazier, Wen Xu, Andrew T. Lambe, Megan S. Claflin, Brian M. Lerner, John T. Jayne, Douglas R. Worsnop, Manjula R. Canagaratna, and Gabriel Isaacman-VanWertz


Interactive discussion

Status: closed

Comment types: AC – author | RC – referee | CC – community | EC – editor | CEC – chief editor | : Report abuse
  • RC1: 'Comment on amt-2021-164', Anonymous Referee #1, 16 Jun 2021
    • AC1: 'Reply on RC1', Chenyang Bi, 10 Sep 2021
  • RC2: 'Comment on amt-2021-164', Anonymous Referee #2, 13 Jul 2021
    • AC2: 'Reply on RC2', Chenyang Bi, 10 Sep 2021

Peer review completion

AR: Author's response | RR: Referee report | ED: Editor decision | EF: Editorial file upload
AR by Chenyang Bi on behalf of the Authors (10 Sep 2021)  Author's response   Author's tracked changes   Manuscript 
ED: Publish as is (25 Sep 2021) by Bin Yuan
AR by Chenyang Bi on behalf of the Authors (26 Sep 2021)
Short summary
Iodide-adduct chemical ionization mass spectrometry (I-CIMS) has been widely used to analyze airborne organics. In this study, I-CIMS sensitivities of isomers within a formula are found to generally vary by 1 and up to 2 orders of magnitude. Comparisons between measured and predicted moles, obtained using a voltage-scanning calibration approach, show that predictions for individual compounds or formulas might carry high uncertainty, yet the summed moles of analytes agree reasonably well.