Articles | Volume 12, issue 3
Research article
14 Mar 2019
Research article |  | 14 Mar 2019

Ultrasonic nebulization for the elemental analysis of microgram-level samples with offline aerosol mass spectrometry

Rachel E. O'Brien, Kelsey J. Ridley, Manjula R. Canagaratna, John T. Jayne, Philip L. Croteau, Douglas R. Worsnop, Sri Hapsari Budisulistiorini, Jason D. Surratt, Christopher L. Follett, Daniel J. Repeta, and Jesse H. Kroll


Interactive discussion

Status: closed
Status: closed
AC: Author comment | RC: Referee comment | SC: Short comment | EC: Editor comment
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Peer-review completion

AR: Author's response | RR: Referee report | ED: Editor decision
AR by Rachel O'Brien on behalf of the Authors (25 Jan 2019)  Author's response   Manuscript 
ED: Referee Nomination & Report Request started (28 Jan 2019) by Keding Lu
ED: Publish as is (11 Feb 2019) by Keding Lu
AR by Rachel O'Brien on behalf of the Authors (20 Feb 2019)  Author's response   Manuscript 
Short summary
Analysis of the elemental composition of organic mixtures can provide insights into the sources and aging of environmental samples. Here we describe a method that allows characterization of this type of material using micrograms of material by a combination of a small-volume ultrasonic nebulizer and an aerosol mass spectrometer. This technique enables rapid analysis of complex organic mixtures using approximately an order of magnitude less sample than standard analyses.